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Tag: Sugar

Hyperglycemia and Chemoresistance in Breast Cancer: From Cellular Mechanisms to Treatment Response

December 9, 2025
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| Cancer - Breast, Cancers, Chemotherapy

Comment: A solid, though non-systematic, review that effectively compiles preclinical evidence showing how hyperglycemia drives chemoresistance via metabolic reprogramming (the Warburg effect). Crucially, it reminds us that aggressive glycemic control is a clinically relevant intervention. The Wonk Debate – Audio Critique & Clinical Commentary: Summary: Clinical Bottom Line This narrative review synthesizes preclinical and clinical […]

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Hyperglycemia during Adjuvant Chemotherapy as a Prognostic Factor in Breast Cancer Patients without Diabetes

December 9, 2025
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| Cancer - Breast, Cancers, Chemotherapy

Comment: This study again reinforces that we need to view blood sugar through the lens of oncologic outcome. Hyperglycemia is a driver of cancer recurrence, so modulating sugar intake during chemotherapy is a low-toxicity, low-cost strategy that somehow is still controversial despite all the research supporting it. Since sugar consumption is the primary lever for […]

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Simple sugar intake and cancer incidence, cancer mortality and all-cause mortality: A cohort study from the PREDIMED trial

December 7, 2025
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| Cancers

🍏Comment: This study, stemming from the PREDIMED trial, suggest that it’s not the total amount of simple sugar that seems to drive cancer risk and mortality in this high-risk population, but the physical form it’s consumed in. It isolates liquid sugars (like those in fruit juice and presumably sugary drinks) as the significant culprits, with a […]

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This work is licensed under CC BY-NC 4.0 Excludes third-party study data & figures.

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