Cancers – Page 11 – OncWonk – Dr Bier's Oncology Research Reviews

Effect of soy isoflavones on breast cancer recurrence and death for patients receiving adjuvant endocrine therapy

October 25, 2025

Comment: This article shows a benefit to soy intake for ER+/PR+ patients taking AI medications, but not with tamoxifen. Summary: Clinical Bottom Line This prospective cohort study found a significant association between high dietary soy isoflavone intake (defined as >42.3 mg/day) and a reduced risk of breast cancer recurrence among postmenopausal patients receiving adjuvant endocrine […]

Soy Food Intake and Breast Cancer Survival

October 25, 2025

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| Cancer - Breast

Comment: This study shows that in breast cancer patients, soy consumption was associated with reduced rates of both recurrence and death from breast cancer, as well as improved overall survival, not only breast cancer specific survival. As always, the focus needs to be on overall survival as the important metric, and this one shows that […]

Dietary Supplement Use During Chemotherapy and Survival Outcomes of Patients With Breast Cancer Enrolled in a Cooperative Group Clinical Trial (SWOG S0221)

October 23, 2025

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| Cancer - Breast, Supplements

Comment: This article was a source of great concern to patients and oncologists when it first came out, and still is. As published in ASCO:“Using antioxidants and other dietary supplements before and during adjuvant chemotherapy for breast cancer may increase the risk of recurrence and “to a lesser extent, death,” according to an analysis of […]

A Review of the Clinical and Epidemiologic Evidence Relevant to the Impact of Postdiagnosis Isoflavone Intake on Breast Cancer Outcomes

October 5, 2025

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| Cancer - Breast, Nutrition

Comment: The evidence supporting the safety of soy has been building for a long time, yet the damaging myth that it is ‘dangerous’ persists—driven almost entirely by preclinical models. This 2025 review serves as a definitive corrective. It confirms that in human patients, soy intake is not only safe but consistently associated with better outcomes—specifically […]

Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD

September 20, 2025

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| Cancer - Colon, Nutrition

COMMENT: The application to sugary drinks is obvious, however I would extend it to fruit and fruit juice consumption as well which both have high amounts of fructose and glucose, as well as sucrose. As examples: Fruit / Juice Serving Size Fructose (g) Glucose (g) Total Sugars (g) Whole Fruits Apple […]