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NatWonk – Naturopathic Research Reviews
NatWonk – Naturopathic Research Reviews
Comment: This study presents a very practical and appealing option for managing advanced HER2-negative breast cancer in the palliative setting. The key takeaway is the dual advantage of this all-oral metronomic regimen: it demonstrates clinically relevant activity while maintaining an exceptionally low toxicity profile. However, the regimen’s main strength is its safety and convenience. Being […]
Comment: This study showed that supplementing with a soy protein isolate didn’t impact PSA levels. However, a critical piece of context for this null finding is the dose they used. The 41 mg/day of total isoflavones used in this trial sits at the absolute low end of the 40-80 mg/day range typically tested in prostate cancer […]
Comment: This is an interesting and potentially alarming one. I’m sure we’ve all noted times where a stable patient started progressing after getting an infection. This study shows an association of SARS-CoV-2 infection with a nearly two-fold increase in cancer-specific mortality (UK Biobank) and a 44% higher rate of lung metastases in breast cancer patients […]
Comment: This meta-analysis is a classic example of how pooling heterogeneous and methodologically different studies can create confusion. In general I am always suspicious of meta-analyses for that reason. Although it is possible that there is a biological reason for the studies on Asian women to be different than on Western, it is also possible […]
Comment: Two underlying assumptions of the repurposed drug movement is that since the medications are already approved they are both safe and can achieve clinically meaningful levels. The issue is that using an anti-parasitic short term is very different than trying to get higher blood levels long term. This trial shows delayed, grade 3 liver […]
Comment: For years, people have been inappropriately scared of soy both in terms of causing breast cancer and negatively impacting progression once they have it. There is a group of people out there who are continuing to promote that despite all evidence to the contrary. The key finding of this study is not just that […]
Comment: This meta-analysis of observational studies serves as another robust rebuttal to the lingering concerns regarding soy’s impact on male hormonal health. It shows a significant reduction in prostate cancer risk in those with the highest consumption. With data representing over 266,000 participants and 21,000 cases, the findings suggest that soy isoflavones function as protective […]
Comment: This study presents a provocative and counter-intuitive finding that directly challenges the conventional wisdom surrounding soy and prostate cancer. While many previous studies have suggested a protective role for soy, this large, prospective Japanese cohort finds the opposite: the highest intake of soy foods was associated with a 76% increased risk of prostate cancer […]
Comment: A common question from breast cancer survivors is whether soy is safe to eat. This post breaks down a 2012 Chinese study that explored this topic. The researchers found a positive association between high soy intake and improved survival for breast cancer patients, particularly those with ER-positive tumors. Summary: Clinical Bottom Line This prospective […]