Comment: A common question from breast cancer survivors is whether soy is safe to eat. This post breaks down a 2012 Chinese study that explored this topic. The researchers found a positive association between high soy intake and improved survival for breast cancer patients, particularly those with ER-positive tumors. Summary: Clinical Bottom Line This prospective […]
Comment: A study looking at the impact of phytonutrients, including soy and tea. The strongest evidence is for soy isoflavones. Summary: Clinical Bottom Line This systematic review of observational studies provides “Probable” evidence that higher soy isoflavone consumption is associated with a reduced risk of breast cancer recurrence, particularly for postmenopausal and ER-positive survivors. Similarly, […]
Comment: This article shows a benefit to soy intake for ER+/PR+ patients taking AI medications, but not with tamoxifen. Summary: Clinical Bottom Line This prospective cohort study found a significant association between high dietary soy isoflavone intake (defined as >42.3 mg/day) and a reduced risk of breast cancer recurrence among postmenopausal patients receiving adjuvant endocrine […]
Comment: This study shows that in breast cancer patients, soy consumption was associated with reduced rates of both recurrence and death from breast cancer, as well as improved overall survival, not only breast cancer specific survival. As always, the focus needs to be on overall survival as the important metric, and this one shows that […]
Comment: This article was a source of great concern to patients and oncologists when it first came out, and still is. As published in ASCO:“Using antioxidants and other dietary supplements before and during adjuvant chemotherapy for breast cancer may increase the risk of recurrence and “to a lesser extent, death,” according to an analysis of […]
Comment: This is a study that is often cited by people who advocate for fenbendazole in cancer treatment, however it doesn’t take much looking to see that not only does it not support it’s use, but there are clear potential danger signals. First, this is a mouse study with a total of 19 mice across […]
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Comment: The evidence supporting the safety of soy has been building for a long time, yet the damaging myth that it is ‘dangerous’ persists—driven almost entirely by preclinical models. This 2025 review serves as a definitive corrective. It confirms that in human patients, soy intake is not only safe but consistently associated with better outcomes—specifically […]
Comment: The trend towards drug repurposing for cancer treatment has a basic underlying assumption that it is safe, even if not proven effective. This study shows that may not be the case with 4/10 patients showing hyperprogression. Summary: Clinical Bottom Line This early-phase study was stopped prematurely due to a complete lack of efficacy […]
Comment: Interesting mechanism regarding the depletion of arginine, and restoration of function with arginine or citrulline supplementation. Does that indicate that supplementing with those would benefit people on immunotherapy regardless – there is data to support that it does, see here. Summary: Sucralose Consumption Ablates Cancer Immunotherapy Response Through Microbiome Disruption Clinical Bottom Line This […]
